Editorial While the opt‑out model represents an important policy shift, evidence shows that legislation alone cannot deliver the cultural and behavioural change required to increase donation rates. T he editorial argues that meaningful progress depends on strengthening public understanding, normalising family conversations, supporting clinicians in sensitive communication, and building trust through transparency and community engagement. By reframing organ donation as an…

To synthesise current evidence on professional burnout among physicians, with a focus on epidemiology, causes, clinical manifestations, diagnostic approaches, prevention strategies, and management. The review also examines the role of work–life balance as a modifiable determinant of burnout risk.

Design: Narrative review.

Methods: A targeted literature search was conducted using MEDLINE, Embase, PsycINFO, and grey literature sources.…

Objectives: To synthesise current evidence on Bowel motility and Bladder Disorders (BBD) and menstrual disorders across early childhood through adolescence, highlighting shared pathophysiology, psychosocial determinants, and opportunities for integrated, holistic management. T he review emphasises developmental transitions, family context, and system‑level approaches relevant to paediatric and adolescent care.

Design: Narrative review of…

In today’s world, herbal or “natural” insecticides are generally considered benign, but their toxic potential remains inadequately recognized. We report the case of a 75-year-old man who voluntarily took a commercially available herbicide containing terpenes, alkaloids, lactones and emulsifiers. He presented himself to the emergency department with repeated vomiting, altered sensors, progressive cyanosis and hypoxia, which did not improve despite additional oxygen. Initial clinical results…

Introduction: Primary Hyperparathyroidism (PHPT) is frequently associated with vitamin D deficiency, which may exacerbate hyperparathyroidism, hypercalcemia, and bone complications.

Objective: To assess vitamin D status in patients with PHPT and analyze its biological and clinical impact.

Patients and Methods: A retrospective study conducted over seven years (2015-2022) including patients hospitalized for PHPT. Serum…

Introduction: Multiple Endocrine Neoplasia type 2A (MEN2A) is a rare genetic disorder primarily characterized by Medullary Thyroid Carcinoma (MTC) and Primary Hyperparathyroidism (PHPT) in 20 to 30% of cases. PHPT is rarely the initial presenting symptom. This study aims to describe the clinical and biological features of PHPT in MEN2A to improve understanding and management of this condition.

Patients and Methods: This is a retrospective…

Ectopic mediastinal parathyroid adenoma is a significant cause of refractory and recurrent primary hyperparathyroidism. Although rare compared to cervical locations, this pathology presents particular diagnostic and therapeutic challenges. We report a series of three cases illustrating these difficulties, along with favorable outcomes achieved through advanced imaging and appropriate surgical management. An updated literature review is provided to better understand the optimal care for these…

Cowden syndrome is a rare genetic disorder, often linked to PTEN gene mutations, characterized by a predisposition to various cancers. We report the case of a patient presenting with papillary thyroid carcinoma revealing the syndrome, highlighting the importance of early diagnosis and multidisciplinary management.

Autoimmune Pancreatitis (AIP) is a rare cause of chronic pancreatitis, accounting for approximately 2% of cases [1]. The association between Slowly Progressive Type 1 Diabetes (SPT1D) and AIP is poorly described in the literature [2]. We report the case of a patient presenting with concomitant AIP and type 1 diabetes, highlighting the possible involvement of a common autoimmune process affecting both the endocrine and exocrine pancreatic functions.

Pulmonary Vascular Hypertension (PVH) in early childhood is uncommon and often overlooked when children present with acute severe wheeze. We report a complex case of a 2‑year‑old girl with colorectal motility disorder, micronutrient deficiencies, immune dysfunction, and recurrent viral‑induced wheeze who developed sudden severe respiratory distress. Her presentation mimicked status asthmaticus but was ultimately attributed to foreign body aspiration and unrecognised pulmonary vascular…