Research Article 10.5281/zenodo.19763230

Continuous - Time Markov Modeling of Durvalumab Dynamics after Chemoradiotherapy in Stage III NSCLC (PACIFIC Era): Development, Validation, and Extrapolation

Zurita AJW, Ruíz MAG, Carmona DM, et al.

Background: Immunotherapy in un-resectable stage III NSCLC shows delayed treatment effects and time-varying hazards that challenge proportional-hazards assumptions. We developed a Continuous-Time Markov Chain (CTMC) model - with piecewise hazards - to capture the temporal…...

Research Article 10.5281/zenodo.20002546

An Investigation of the Association Between Periodontal Disease and Cutaneous Melanoma: A Case-Control Study in Greek Adults

Nikolaos Andreas Chrysanthakopoulos, Eleftheria Vryzaki, Vassiliki Vazintari

Background/Aim: Previous investigations have showed biological linkages between Periodontal Disease and various types of cancer, such as oral/head and neck cancer, gastric cancer, esophageal cancer, kidney cancer, lung cancer, prostate cancer, hematological malignancies, and…...

Mini Review 10.5281/zenodo.19689672

Bacteriolysis Destruction for S. Aureus and E. Coli Peptidoglycan Cell Wall by Metal Salts and Metal-Based Compounds/Alloy Materials

Tsuneo Ishida, Reiko Kobayashi

Antimicrobial and bacteriolytic PGN cell wall destruction, hydrolysis, decomposition, and cleavage activities by metal salts, metal-based compounds/alloy materials have been extensively elucidated against S. aureus and E. coli.

Anti-microbial activity on metal salts:…...

Case Blog 10.5281/zenodo.20004720

Evaluation of Intelligent Flight Control Systems for Loss of-Control Recovery and Prevention

Mahabub Sultan, Nikunjun Sarker Akash, Xue Hongjun

Recent advancements in the field of loss-of-control recovery and prevention include fault-tolerant control, improved pilot training, and cockpit automation. The benefits of fault-tolerant "intelligent," flight control systems were demonstrated by the Flight Mechanics Action Group on…...

Research Article 10.5281/zenodo.19761316

Foodborne Risks Associated with Multidrug-Resistant Escherichia coli and Staphylococcus aureus Isolated from Milk

Alhanouf S. Almutairi, Nazek Al-Gallas, Mohamed Abdelrahman, et al.

Although milk is a vital part of the human diet, foodborne bacteria, especially those with antibiotic resistance, may spread through it. The purpose of this study was to assess the foodborne risks related to Staphylococcus aureus and multidrug-resistant (MDR) Escherichia coli that were isolated…...

Perspective 10.5281/zenodo.19765318

Six Years on: Persistent Structural Gaps in COVID-19 Pandemic Policy and Implications for Future Global Health Crises

Malik Sallam

Six years after the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) as a global pandemic, several key scientific and policy questions remain unresolved— an unsettling state of affairs given the inevitability of future pandemics. This Perspective examines five domains…...

Mini Review 10.5281/zenodo.19765113

Journal Publication Integrity Issues: Preserving Academic Communication's Credibility: An Overview

Nnodim Johnkennedy

The credibility of science and the advancement of knowledge depend on scholarly publishing's integrity. Trust is the foundation of the whole publication process, from data collection and article drafting to peer review and editorial decision-making. However, a number of integrity issues threaten…...

Research Article 10.5281/zenodo.19760006

Production of Starch-Based Bioplastic from the Mixture of Potato and Cassava Peel Wastes Starch Using Glycerol as Plasticizers: A Comparison on the Effect of CaCO3 and HCl as Fillers

Nasir A. S, Mahmud A, Aliyu A

This study investigates the production of starch-based bioplastics from the mixture of potato and cassava peel waste starch using glycerol as plasticizer (20% wt/v) and comparing reinforcement with calcium carbonate and hydrochloric acid (4% wt/wt of filler to starch). The potato and cassava…...

Case Report 10.5281/zenodo.19689466

Thoracic Intradural Extramedullary Arachnoid Cyst Presenting with Neurogenic Claudication

Hakan AK, Sedanur Özgül

Background: Spinal arachnoid cysts are rare, benign cerebrospinal fluid–filled lesions that may cause spinal cord or nerve root compression. They are most frequently located in the thoracic region and typically present with a slow, insidious clinical…...