Background: Labour induction is increasingly common, and misoprostol is widely used due to its efficacy, affordability, and stability. The optimal administration route remains debated, particularly regarding efficacy and safety.

Objective: To compare the efficacy and safety of low-dose oral versus vaginal misoprostol for labor induction and evaluate associated maternal and neonatal outcomes.

Methods: Pregnant women…

Background: Female reproductive hormones exert systemic effects extending beyond reproductive physiology to influence hematopoiesis, immune regulation, endothelial integrity, and haemostatic balance. Cyclical and life‑stage hormonal variations significantly alter haematological and coagulation parameters.

Objective: To systematically review and synthesize evidence on the association between female reproductive hormones and haematological and…

Background: Severe malaria remains a leading cause of morbidity and mortality worldwide, particularly among vulnerable populations such as the elderly and individuals with comorbidities. The interaction between malaria, dehydration, hypertension, and stroke can accelerate multiorgan dysfunction through complex hematological, haemostatic, and microvascular mechanisms.

Case Presentation: We report the case of an 85-year-old hypertensive female with…

Background: In May 2026, the World Health Organization (WHO) reported a multi-national cluster of Andes hantavirus (ANDV) infections linked to the cruise vessel M/V Hondius. The outbreak generated international concern because ANDV is associated with hantavirus pulmonary syndrome (HPS), a severe zoonotic disease with reported case-fatality rate (CFR) of 35-50%, despite limited person-to-person transmission. This rapid mini-review aimed to examine the virologic,…

Background: Digital feedback systems are increasingly integrated into school-based cardiopulmonary resuscitation (CPR) training. Prior research has largely emphasized mean performance outcomes, whereas assessment theory suggests that distributional characteristics—particularly lower-tail reliability—may be equally relevant in safety-critical competence contexts.

Purpose: This study examined whether different instructional configurations under…

The present short communication serves to justify important relations of phylo- and ontopathogenic models elaborated by us to the broadened versions of gerontology and endocrinology, culminating in our recently offered, more general concept of ontogenetic bioregulation.

Keywords: Conceptual Models; Ontogeny; Phylogeny

Urticaria is a heterogeneous dermatological disorder characterized by transient wheals, angioedema, and pruritus, affecting up to 20% of individuals at least once during their lifetime. While many cases are idiopathic, a substantial proportion of patients report seasonal variation in disease activity, suggesting a contributory role of environmental factors. This narrative review examines the influence of humidity and pollen—two key seasonal environmental modifiers—on the onset and…

Computerized tomography (CT) technique popularity in China led to a new phenomenon— pulmonary nodules in a lot of adults. Effective therapeutics may base on new diagnostic techniques, surgery and drug study. As a new challenge, the diagnostic and therapeutic relations are bridge to narrow to mistake margins and patient incurability. This Article addresses the rollout of new diagnostic-therapeutic techniques and availability for this pattern of pulmonary disease in wide ranges.

Microalgae represent an outstanding renewable resource for the sustainable production of biohydrogen, owing to their rapid growth rates, efficient carbon fixation, and adaptability to various aquatic environments, as well as their low nutritional demands and minimal land requirements. Nonetheless, their commercial viability is hindered by challenges such as low hydrogen yields and high production costs. Recent advancements have actively addressed these challenges by prioritizing the…

Diabetic neuropathy (DN) is a prevalent and debilitating chronic consequence of diabetes mellitus, impacting over 50% of patients with long-standing illness. It includes a wide range of illnesses that affect peripheral and autonomic nerves, which can cause loss of sensation, neuropathic pain, autonomic dysfunction, and a higher risk of foot ulcers and amputations. Even though diabetes treatment has gotten better, DN is still not diagnosed or treated well enough, mostly because its aetiology…