Epidermolysis bullosa (EB) comprises a heterogeneous group of inherited mechanobullous disorders characterised by skin fragility and blister formation following minimal trauma [1–3]. We report a female neonate presenting with localised blistering on the dorsum of the right foot and over the heel, ultimately diagnosed with epidermolysis bullosa simplex (EBS). Early multidisciplinary involvement, meticulous wound care, and parental counselling were central to management [8, 9]. This case…

We describe a mother–infant dyad. The mother, a 16‑year‑old teenager, presented with a background of lifelong chronic constipation, recurrent abdominal discomforts, pain and distension, and malabsorption. The patient presented suddenly with progressive gait disturbance, and profound anemia. She was diagnosed with hypoganglionosis on full‑thickness biopsy and SCD on MRI. Her infant daughter presented at 7 months with acute ileocolic intussusception, requiring radiological reduction. Both…

Introduction: Von Hippel–Lindau (VHL) disease is an autosomal dominant genetic disorder predisposing to the development of benign and malignant tumors, notably pheochromocytomas, which are often bilateral and of early onset.

Objective: To describe the clinical, biological, radiological, and evolutionary characteristics of patients with bilateral pheochromocytomas associated with VHL disease and to compare our results with the literature…

Chalcogenide glasses are of huge attention due to these intriguing optical and electrical characteristics. The physical parameters of Se90-x Te5 Sn5 Inx (0≤x≤9) glassy alloys have been thoroughly examined in this work. In this system I have theoretical evaluated density (ρ), molar volume (Vm ), lone pair of electrons (LP), average coordination number , number of constraints (Nc ) and mean bond energy for this system. The evaluated values of Vm , LP, and stoichiometry (R) fall with increasing…

Benign Paroxysmal Positional Vertigo (BPPV) is the most common peripheral vestibular disorder and is especially prevalent among older adults. While most cases are idiopathic, secondary BPPV following otitis media has gained increasing recognition. This case report describes a 63-year-old female with bilateral posterior canal BPPV involving mixed mechanisms(Right-sided cupulolithiasis and left-sided canalithiasis) occurring one year after medically treated otitis media. The diagnosis was…

Background: Current stroke rehabilitation focuses on motor output parameters (strength, spasticity, motor recovery) without directly assessing neurovascular–neuromuscular coupling (NMC)—the synchronization between neural drive, muscle activation, and local blood flow. Emerging neuroscience indicates that impaired microvascular perfusion–muscle activation coupling represents a fundamental pathophysiological mechanism limiting motor recovery post-stroke, yet no standardized…

Background: Current stroke rehabilitation treats limbs largely independently, despite mounting evidence that bilateral sensorimotor synchronization—the coordinated temporal and spatial control of bilateral limb movement—represents a core physiological requirement for functional recovery. No standardized physiotherapy assessment quantifies interlimb phase lag, bilateral proprioceptive integration, or force-sharing asymmetry as measurable physiological…

Introduction: Testicular regression syndrome (TRS) is a rare cause of disorders of sex development in 46,XY individuals. It corresponds to the partial or complete disappearance of testicular tissue following initially normal male differentiation.

Objective: To describe the clinical, biological, radiological, and evolutionary characteristics of a series of 7 patients followed for TRS, and to compare them with recent literature…

Background: Effective postoperative pain control is a key determinant of recovery following laparoscopic surgery. Transversus Abdominis Plane (TAP) block is widely used as part of multimodal analgesia to reduce postoperative pain and opioid consumption. However, real world evidence comparing analgesic outcomes associated with TAP block use in routine clinical practice remains limited.

Aim: To assess the association between the use of TAP block…

Sustainable intensification of rainfed rice systems in sub-Saharan Africa is constrained by low soil fertility and limited access to mineral fertilizers. Integrated nutrient management that combines organic and mineral sources offers a promising pathway to enhance productivity and soil health. A field experiment was conducted in Nkolbisson, Cameroon, to evaluate the effects of pigeon pea (Cajanus cajan L.) biomass and mineral fertilizers on the growth, yield, and soil properties of rainfed…