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Review Article | Open Access

Published on: 15 Oct 2026

Article ID: wjtr.2026.j1502

Pediatric Surgical Thyroid Disorders: Comprehensive Review of Congenital, Benign, and Malignant Thyroid Disease with Contemporary Advances in Molecular Diagnostics, Precision Surgery, and Survivorship
Khatri LK 1 More AB 2 Govani PS 3 Zaparackaite I 4 More BB 5 Singh SJ 6 Swamy KB 6 Mehta AR 7 Midha PK 7 Patel RV* 8

Background: Thyroid disorders requiring surgical intervention are uncommon in children but represent a unique spectrum of diseases characterized by higher malignancy rates, distinct molecular profiles, and specific perioperative considerations compared with adults.

Objective: To review the epidemiology, clinical presentation, diagnostic evaluation, surgical indications, operative management, complications, and outcomes of pediatric thyroid…

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Review Article | Open Access

Published on: 10 Oct 2026

Article ID: wjtr.2026.j1002

State of Art Antithyroid Drug-Induced Neutropenia and Agranulocytosis
Emmanuel Andrès* 1,2,3 Xavier Jannot 1,2 Jean-Edouard Terrade 1,2 Khalid Serraj 4 Noel Lorenzo-Villalba 1,2

Antithyroid Drugs (ATDs) - principally carbimazole, methimazole (thiamazole), and propylthiouracil - remain central to the treatment of hyperthyroidism but can rarely cause idiosyncratic neutropenia and agranulocytosis, a potentially fatal adverse drug reaction. Agranulocytosis is conventionally defined by an absolute neutrophil count below 0.5×109/L and may develop abruptly after a previously normal blood count. This Seminar reviews contemporary epidemiology, drug- and patient-related risk…

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Systematic Review | Open Access

Published on: 09 Mar 2026

Article ID: wjtr.2026.c0901

Use of Levothyroxine in Patients with Subtotal Thyroidectomy: A Systematic Review Levothyroxine After Subtotal Thyroidectomy
Llerena Freire LF* 1

Introduction: Subtotal thyroidectomy preserves glandular tissue intending to maintain hormonal autonomy; however, the viability of the remnant is unpredictable, complicating postoperative pharmacological management.

Objective: To analyze available scientific evidence on the indication, dosage regimens, and clinical outcomes of levothyroxine use in patients undergoing subtotal thyroidectomy.

Methodology: A systematic…

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Case Report | Open Access

Published on: 14 Nov 2025

Article ID: wjtr.2025.k1402

Agenesis of Thyroid Isthmus Associated with Thyroid Papillary Carcinoma: A Rare Case
Güvenç Diner* 1 Güven Erdoğrul 1 Mustafa Ugur 2

Anatomical anomalies of the thyroid gland are very important for the management of thyroidectomy operations. The thyroid gland consists of two lobes and the isthmus connecting them. The absence of the isthmus of the thyroid gland is defined as thyroid isthmus agenesis and very few cases have been reported in the literature. In the present case, isthmus agenesis was detected during thyroidectomy operation performed due to suspicion of malignancy. Caution should be exercised in terms of…

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Research Article | Open Access

Published on: 09 Jun 2025

Article ID: wjtr.2025.f0901

The Influence of Physical Activity on Perceived Stress in Thyroid Patients in India
Ms. Saaniya Memon* 1 Ms. Aishwarya Sibey 1

Thyroid disorders, including hypothyroidism and hyperthyroidism, are among the most prevalent endocrine conditions in India, often leading to persistent psychological symptoms such as perceived stress. While pharmacological treatments address hormonal imbalances, many patients continue to experience emotional distress. This study investigates the relationship between physical activity and perceived stress among Indian thyroid patients, aiming to explore the potential of exercise as a…

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