WebLog Journal of Endocrinology and Diabetes

Introduction: Cushing’s syndrome (CS) during pregnancy is a rare and complex condition due to the overlap of symptoms with normal physiological changes during pregnancy and the associated maternal and fetal risks.

Objective: To describe three cases of Cushing’s syndrome diagnosed during or shortly after pregnancy, detailing clinical characteristics, diagnostics, management, and outcomes, alongside a review of recent…

Introduction: Oculomotor palsies are a rare manifestation of focal diabetic neuropathies. Their clinical presentation may mimic serious neurological conditions, making diagnosis challenging. Objective: To report a series of four cases of oculomotor palsy in diabetic patients and to analyze their clinical, diagnostic, therapeutic, and evolutionary characteristics in light of the literature.

Patients and Methods: A retrospective descriptive study…

Introduction: The association between type 1 diabetes (T1D) and epilepsy has been reported more frequently than in the general population. However, the exact pathophysiological link remains poorly understood.

Objective: To describe the clinical characteristics of patients presenting with an association of T1D and epilepsy and to discuss the possible pathophysiological mechanisms in light of data from the…

Introduction: Primary hyperparathyroidism (PHPT) is one of the most common endocrine disorders, characterized by inappropriate secretion of parathyroid hormone (PTH), leading to disturbances in calcium–phosphate metabolism and multisystem complications.

Objective: To determine the prevalence and profile of clinical, biological, and radiological complications of PHPT in a Moroccan hospital-based cohort.

Materials and…

Introduction: Celiac disease (CD) is an autoimmune enteropathy triggered by gluten ingestion in genetically predisposed individuals. It is frequently associated with type 1 diabetes (T1D), with a prevalence significantly higher than that observed in the general population. Diagnosis usually relies on positivity of specific autoantibodies and histological confirmation. However, seronegative forms can be observed, notably in T1D patients, making diagnosis more…

Introduction: Graves’ disease is an autoimmune disorder characterized by hyperthyroidism related to the presence of thyroid-stimulating hormone receptor antibodies. Long considered protective against thyroid cancer, it is now recognized as potentially associated with differentiated thyroid carcinomas, mainly papillary carcinoma.

Objective: To describe the clinical, histological, therapeutic, and outcome characteristics of thyroid carcinomas…

Turner syndrome (TS) is a rare chromosomal disorder characterized by partial or complete monosomy X. The presence of Y chromosome material, particularly the sex-determining region Y(SRY) gene, has important clinical implications due to the increased risk of gonadoblastoma. We report two cases of young women with Turner syndrome harboring Y chromosome material detected by fluorescence in situ hybridization (FISH), illustrating the phenotypic variability, diagnostic challenges, and therapeutic…

Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by inappropriate parathyroid hormone (PTH) secretion leading to chronic hypercalcemia. Acute pancreatitis is a rare but potentially severe complication of PHPT. We report three cases in which acute pancreatitis was the revealing manifestation of primary hyperparathyroidism. These observations emphasize the importance of systematically investigating metabolic causes, particularly hypercalcemia, in cases of acute…

The synchronous occurrence of laryngeal squamous cell carcinoma (LSCC) and papillary thyroid carcinoma (PTC) is rare and is most often discovered incidentally on histopathological examination of surgical specimens. We report a series of four cases illustrating this uncommon association, focusing on clinical presentation, histological findings, therapeutic management, and outcomes. Prognosis mainly depends on the laryngeal squamous cell carcinoma, while papillary thyroid carcinoma generally…

The association between primary hyperparathyroidism (PHPT) and non-medullary thyroid carcinoma is rare and is most often discovered incidentally during surgical exploration or histopathological examination. We report a case series of three patients presenting with thyroid carcinoma associated with primary hyperparathyroidism. We describe the clinical presentation, imaging findings, surgical management, and histopathological features. This coexistence raises pathophysiological questions and…