Dr. Caroline Amuche Okoli PhD, PGDE, FMLSCN

Senior Lecturer | Clinical Biochemistry & Medical Microbiology Specialist | Infectious Disease Diagnostics Innovator

Dr. Caroline Amuche Okoli stands at the forefront of medical diagnostics and infectious disease research in Nigeria. A respected Senior Lecturer and multidisciplinary scientist at the University of Jos, she brings together expertise in Chemical Pathology, Clinical Biochemistry, Medical Microbiology, Genomics, and Bioinformatics to drive innovative approaches to disease detection, monitoring, and prevention.

With a professional journey spanning more than two decades, Dr. Okoli has transitioned from frontline clinical laboratory practice to academic leadership, earning a reputation for excellence in malaria diagnostics, biochemical and molecular marker discovery, neonatal health research and host-pathogen interaction studies. Her scholarly output includes over 30 peer-reviewed publications and books, widely cited for their contributions to understanding biochemical responses in malaria, anti-microbial resistance, bioinformatics, trace element dynamics, and pediatric infectious diseases. She is the author of the influential textbook New Standards in Laboratory Diagnosis of Malaria (2018; Revised Edition, Cambridge Scholars Publishing UK, 2024), demonstrating her commitment to advancing evidence-based diagnostic practices across Africa. Beyond publishing, Carol plays an active role in shaping scholarly discourse. She serves as a peer-reviewer to some journals such as Nigerian Medical Journal, Sahel Medical Journal, American Journal of Laboratory Medicine where she also currently serves as a member of the editorial board. Dr. Caroline is the online lecturer of the novel  Pathogenomics course - an online free genomics & bioinformatics course powered by Distinction Artificial Intelligence. Carol serves the Nigeria communities through mass enlightenment on healthy living and executes free laboratory malaria, hepatitis, blood group etc testings. She has earned some grant awards including the  TETFUND/NRF 2023 grant award for,  “Development of PI4K barcode as a genotyping tool for determining population genetic structure pattern of Plasmodium falciparum, transmission dynamics and differentiating reinfection from recrudescence”.

• Infectious Diseases and Diagnostics
• Pathogenomics
• Neonatal/Pediatric Health Research
• Host-pathogen Interaction
• Epidemiology and Public Health

• Caroline Okoli (2026).Evaluating primer and probe mismatch tolerance in an Influenza A matrix gene RT qPCR using contemporary human and zoonotic strains. doi: https://doi.org/10.64898/2026.02.23.707407 (preprint)
• Okoli, CA., Alex, E., Nweze NP., Bosu, B (2026)."Evolutionary Insight into Global Multi-drug resistance S. aureus Strains isolated from blood: A 16S rRNA-Based Comparative Study of Resistance-Linked Divergence" Iconic Research And Engineering Journals, 9(7) https://doi.org/10.64388/IREV9I7-1713894
• Justine D. Niandat, Caroline A. Okoli (2025). Erythrocyte glucose-6-phosphate dehydrogenase deficiency-induced anaemia in children in Jos, North-Central. African Journal of Laboratory Medicine | Vol 14, No 1 | a2733 | DOI: https://doi.org/10.4102/ajlm.v14i1.2733 |
• Okoli, CA and Johnson, TO (2025). In-silico Assessment of the effects of Hyptis suaveolens as a natural source of Acetylcholine esterase (AchE)- targeting insecticide. DOI: https://doi.org/10.21203/rs.3.rs-6328543/v1 (preprint)
• Ozor Josephat Ejike, Izekwe Kingsley Ikechukwu………. Caroline Amuche Okoli (2025). Effects of Dolutegravir and Protease Inhibitors based Regimen on Renal and Liver Function Markers of HIV Patients Attending Daughters of Charity Hospital Abuja. |Int. J. of Multidisciplinary and Current research, Vol.13 DOI: https://doi.org/10.14741/ijmcr/v.13.1.332
• Okoli CA, Wamu DI, Deffi F, Leshak PD. Evaluation of the impact of malaria and erythrocyte G6PD deficiency on anaemia outcomes among children in Jos Northcentral Nigeria. BMC Res Notes. 2026 Mar 10. doi: 10.1186/s13104-026-07658-0. Epub ahead of print. PMID: 41808221.
• Okoli, C.A., Dadang.J., Daffi.F., Ofakunrin A.O. (2024). Serum zinc and magnesium levels in steady state sickle cell children with or without anaemia attending Jos University Teaching Hospital, North-Central Nigeria. Int. J Clin Biochem. Res. 10(1) 1-7
• Okoli, C.A, Igunnu A., Adebayo J.O., Oguche S., Malomo S.O. (2023) Malaria Diagnostic and Parasite Density Prediction Potentials of Some Serum Biochemical Parameters in Children with Severe Falciparum Malaria Treated with Artesunate/Artemether-Lumefantrine Combination Therapy. Pediatr Ther. 13:515.
• Okoli, C.A., Igunnu, A., Oguche, S., Malomo, S.O. (2023) Response Monitoring and Diagnostic Potentials of Some Serum Electrolytes and Bio-Molecules in Children with Severe Falciparum Malaria Treated with Artesunate/Artemether-Lumefantrine Combination Therapy. J Clin Chem Lab Med. 6:271.
• Okoli, C.A and Numkwem, G. (2023). The Effects of Storage Temperature and Time on Serum Potassium Level. J. Biol. Sci. Biocons.15(1) 42-60
• Okoli, C.A., Igunnu, A., Malomo, S.O., Adebayo, J.O., Oguche, S. (2019). Responses of selected inflammatory, kidney and liver function markers in serum of Nigerian children with severe falciparum malaria to treatment with artesunate/artemether-lumefantrine combination therapy. Afr. J. Biomed. Res. 22:165-177
• Okoli, C.A., Igunnu, A., Malomo, S.O., Oguche, S. (2017). Responses of selected haematological and biochemical parameters to artesunate/artemether-lumefantrin combination therapy in children with severe malaria. Afr.J.Med.Med.Sci. 46:321-332
• Okoli, C.A and Solomon, M. (2014). Prevalence of hospital-based malaria among children in Jos, North central Nigeria. British J. Med. Medical Res. 4(17):3231-3237
• Okoli, C.A. and Enna, M.A. (2014). A cross-sectional study to assess the knowledge, attitude and practice regarding malaria prevention and control measures in central Nigeria. South Afr J Infect Dis. 29(1):37-42
• Okoli, C.A., Solomon, M., Okoli, A.C. (2014). Serum zinc and copper levels in children with Plasmodium falciparum infection in Nigeria. Int. J. of Biochem. Res. Rev. 4(4): 322-332
• Okoli, C. and Solomon, M. (2014). The relationship between zinc and copper in children with malaria. J Med. Appl. Biosci. 6(2):87-100
• Okoli, C.A., Okolo,S.N., Collins, J.C. ( 2013). Plasmodium falciparum infection among neonates in the north central region of Nigeria. J Infect Dev Ctries; 265-371
• Okoli, C.A and Anekwe, G.E. (2013). Determination of co-enzyme Q10 (ubiquinone Q10) in African cat-fish (Clarias gariepinus) liver oil. J Pharm Biomed Sci. 27(27):469-473
• Toma, O. B., Ige, O.O., Abok, I., Onwuanaku, C., Abah, O. R., Donli, A. (2013). Pattern of neonatal admissions and outcome in a tertiary institution in north central Nigeria. J. Med. Trop. 15 (2):121-125
• Onwuanaku, C.A., Okolo, S .N., Ige, K. (2012). The relationship between congenital malaria and birth weight in the highlands of north central Nigeria. Cont. J. Trop. Med. 6(1): 22-26
• Onwuanaku, C.A., Okolo, S.N., Ige,O., Okpe, S.E., Toma, B. (2011). The effects of birth weight and gender on neonatal mortality in north central Nigeria. BMC Res. Notes; 4:562
• Okoli, C.A., Okonji, M.C. Ugoh, S.C, Okolo, S.N., Okoli, A.C., Alu, A.J. (2007). Salmonella specie and total viable bacterial load on roasted chickens sold in Jos, Nigeria. Cont. J. Biomed Sci. 1(2) 11-15
• Okolo, S.N., Chukwu, G.A., Egounui, I., Ezeogu, F.A., Onwuanaku, C.A., Adeleke, O.A., Hassan, H., Ngoe-Nesoah (2006). Oral hygiene and nutritional status of children aged 1-7 years in rural communities of Sokoto State. Ghana Med. J. 40(1) 22-25
• Okolo, S.N., Egbuaba, N.H., Onwuanaku, C., Okonji, M., Ezeogu, A.F., Ogbonna, C. (2004). Blood pressure, body mass index and heart rate of Fulani Children in a rural community of Northern Nigeria. Nig. J. Cardiol. 1(1):47-52
• Okolo, S.N., Adeleke, O.A., Chukwu, G.A., Egbuaba, N.H., Hassan, A., Onwuanaku, C. (2003). Immunization and Nutritional Status Survey of children in selected rural communities of Sokoto State of Nigeria. N J P. 30(4): 123-127
• Okolo, S.N., Ezeogu, A.F., Ogbonna, C., Onwuanaku, C. (2001). Serum and breastmilk levels of selected trace elements in exclusively breastfeeding mothers in Jos, Nigeria: Any difference? J. Med. Trop. 4(2):30-34
• Okolo, S.N., Ada, F., Ogbonna, C., Onwuanaku, C. (2001). Level of calcium, aluminium and chromium in serum of exclusively breastfed infants at 6 months of age in Savanna Region of Nigeria. WAJM. 20(2):13-16
• Okolo, S.N., Onwuanaku, C., Okonji, M., Vauderjagt, D.J., Millson, M., Churchwell, C., Glew, R.H. (2000). Concentration of eight trace minerals in milk and sera of mother-infant pairs in Northern Nigeria. J. Trop. Paed.46(3):160-162
• Okolo, S.N., Vauderjagt, T.J., Vauderjagt, D.J., Okonji, M., Huang, Y.S., Chuang, L.T., Onwuanaku, C., Glew, R.H. (2000). The fatty acid composition of human milk in Northern Nigeria. J. Hum. Lact. 16(1):28-35

• Okoli, C.A. (2012). Congenital malaria and birth- weight in north central Nigeria. ISBN: 978-3-659-21348, Lambert Academic Publishing Company,66121 Saarbrücken, Germany
• Okoli, C.A. (2018). New standards in laboratory diagnosis of malaria. (First Edition) ISBN 978-978-969-729-8, Saniez Books Jos, Nigeria
• Okoli, C.A. (2024). New standards in laboratory diagnosis of malaria (Revised edition). Cambridge Scholars Publishing, UK. ISBN 978-1-0364-1299-9; ISBN (Ebook)978-1-1300-2

• https://orcid.org/0009-0005-0745-1060
• https://www.scopus.com/authid/detail.uri?authorId=55981692400