Junhao CHEN

E-mail: 20231042@kmmu.edu.cn

Google scholar: https://scholar.google.com/citations?hl=en&user=xmA8cmUAAAAJ

Education:

Hokkaido University - PhD in medicine (Immunology) - 10/2026 – 10/2030

Kunming Medical University - Master of Science in surgery - 09/2023 – 06/2026

Kunming Medical University Haiyuan College - Bachelor of Clinical Medicine - 09/2017 – 06/2022

Courses: Cell Biology and Genetics, Medical Statistics, Medical Psychology, Traditional Chinese Medicine, Medical Nutriology, Pharmacology,
Medical Immunology, Medical Microbiology, Histology and Embryology, Biochemistry, Molecular Biology.

Work Background:

The Second Affiliated Hospital of Kunming Medical University - Clinical Researchers - 09/2023 – 06/2030

• Immunology
• Cell Biology and Genetics
• Medical Statistics and Medical Psychology,
• Traditional Chinese Medicine
• Medical Nutriology
• Pharmacology
• Medical Microbiology
• Histology and Embryology
• Biochemistry
• Molecular Biology

• Fu S, Tan Z, Shi H, Chen J, Zhang Y, Guo C, et al. Development of a stemness-related prognostic index to provide therapeutic strategies for bladder cancer. NPJ Precision Oncology. 2024; 8(1):14. (JCR Q1, IF 7.9)
• Fu Y, Chen J, Fu S. Considerations on the efficacy and toxicity of neoadjuvant chemotherapy for BRPC. International Journal of Surgery. 2025; 111(6):4145-4146. (JCR Q1, IF 12.5)
• Chen J, Fu Y, Zhang Z, et al. Nanomaterial-Enhanced T-Cell Immunotherapy: A Promising Strategy for Bladder Cancer. International Journal of Nanomedicine. 2025. (JCR Q1, IF 6.5)
• Chen J, Zhao J, Zhang Z, Zhu X, Zuo J, Nie Z, et al. Blood metabolites as mediators in erectile dysfunction: insights from a multi-center proteomics and genetic study. Frontiers in Pharmacology. 2025. (JCR Q1, IF 4.85)
• Chen J, Zhao J, Wang H, Fu S. Causal relationship between sedentary behavior and urolithiasis: A Bayesian weighted bidirectional Mendelian randomization study. Asian Journal of Surgery. 2025. (JCR Q1, IF 3.5)
• Chen J, Zhao J, Zuo J, Fu Y, Dong H, Shi H, et al. HDL cholesterol esters mediate the genetic link between sedentary behavior and urological cancers: Insights from mediation and validation analyses. Medicine. 2025. (JCR Q2, IF 1.4)
• Chen J, Liu Y, Zhan P, Gao T, Zuo J, Li X, et al. Bayesian-based analysis of the causality between 731 immune cells and erectile dysfunction: a two-sample, bidirectional, and multivariable Mendelian randomization study. Sexual Medicine. 2024. (JCR Q1, IF 2.6)
• Chen B, Zhou Y, Li Z, Chen J, Zuo J, Wang H, Li Z, Fu S. A study on predicting recurrence of non-muscle-invasive bladder cancer within 2 years using mp-MRI. BMC Cancer. 2025. (JCR Q2, IF 3.4)
• Zuo J, Chen J, Tan Z, Wen L, Zhao J, Fu Y, et al. Comprehensive Mendelian randomization and colocalization analysis of plasma proteomics to identify new therapeutic targets for bladder cancer. Journal of Cancer. 2025. (JCR Q2, IF 3.3)
• Zuo J, Chen J, Tan Z, Zhu X, Wang H, Fu S, Wang J. Analysis of long-term trends and 15-year predictions of smoking-related bladder cancer burden in China across different age and sex groups from 1990 to 2021. Discover Oncology. 2025. (JCR Q2, IF 2.8)
• Zhu X, Fu Y, Zhu L, Liu R, Li D, Zhao J, Chen W, Chen J. The role of cerebrospinal fluid metabolites in the pathogenesis of lung adenocarcinoma: An observational study using Mendelian randomization. Medicine. 2025. (JCR Q2, IF 1.4)
• Fu Y, Chen J, Zhu X, Ding M, Wang H, Fu S. Roles and therapeutic potential of the SLC family in prostate cancer: literature review. BMC Urology. (JCR Q3, IF 1.9)
• Zhan P, Chen J, et al. Causal association analysis between 731 immune cells and cystitis: a two-sample bidirectional Mendelian randomization study. Medicine. (JCR Q2, IF 1.4)
• Chen J, Zuo J, Zhao J, et al. Association between 23 psychiatric disorders and bladder cancer: a genetic association analysis. Molecular Psychiatry. 2025. (Under review, JCR Q1, IF 10.1)
• Chen P, Chen J, et al. Targeting cancer-associated fibroblasts in prostate cancer: recent advances and therapeutic opportunities. Cancers. 2025. (JCR Q2, IF 4.4)
• Zhu X, Chen J, et al. Nanomaterials for theranostic management of oral cancer: advances in imaging, biosensing, targeted delivery, and multimodal synergistic therapy. International Journal of Nanomedicine. 2025. (JCR Q1, IF 6.5)
• Chen J, Li X, Zuo J, Fu S. Unraveling the genetic basis of metabolic traits and benign adrenal tumors: a comprehensive causal analysis. International Journal of Clinical and Experimental Pathology. (JCR Q4, IF 1.1)
• Chen J, Zhao J, Fu S. Addressing sample overlap and meta-analysis imbalances in Mendelian randomization: a critical appraisal of protein targets for myocardial infarction. European Heart Journal. 2025. (JCR Q1, IF 35.58)
• Chen J, Wang H, Fu S. Rethinking methodology and data integrity in Mendelian randomization: insights from air pollution and MASLD research. Journal of Hepatology. 2025. (JCR Q1, IF 33.19)
• Zhao J, Chen J, Yao J. Relationship between daily sitting time and kidney stones: analysis of NHANES 2007–2016 data. International Journal of Surgery. (JCR Q1, IF 10.3)
• Qian F, Chen J. Nanomedicine targeting cancer-associated fibroblasts in prostate cancer: from biological mechanisms to integrated theranostic strategies. International Journal of Nanomedicine. (JCR Q1, IF 6.5)
• Wang F, Zhang Z, Chen J. Nanodynamic therapy in colorectal cancer: engineering precision immunotherapy and multimodal synergy. International Journal of Nanomedicine. (JCR Q1, IF 6.5)
• GBD Collaboration Group. Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023. Lancet. (JCR Q1, IF 88.5)
• Dong H, Li H, Chen J, Wang J, Wang H. Comprehensive bioinformatics analysis and validation of the mechanism of glutamic-pyruvic transaminase 2 in bladder cancer. Journal of Cancer. (JCR Q2, IF 3.2)
• Xie J, Mao QY, Chen JH, Shi HJ, Zhan PQ, Wang HF. Efficacy and safety of atezolizumab in the treatment of urothelial carcinoma: a systematic review and meta-analysis. World Journal of Surgical Oncology. (JCR Q1, IF 2.5)
• Wang Z, Shi H, Fu S, Yu L, Dong H, Li H, Chen J, Ding M, Zhang G, Wang H. Prognosis of radical prostatectomy combined with pelvic lymph node dissection in patients with intermediate- and high-risk prostate cancer: a systematic review and single-arm meta-analysis. International Urology and Nephrology. (JCR Q3, IF 1.9)
• Nie Z, Chen J, et al. Treg cells modulate neuroinflammation and behavioral deficits in autism: evidence from MR-based genetic analyses and experimental models. Genetics Part B: Neuropsychiatric Genetics. 2025. (JCR Q3, IF 1.5)
• Zhang Z, Chen J, et al. Unraveling the neuroimmune axis in atopic dermatitis: emerging insights and future directions for targeted neuroimmunotherapy. Journal of Inflammation Research. 2025. (JCR Q2, IF 3.1)
• Chen J, Zuo J, Shi H, Wang H, Fu S. A commentary on 'causal effects of gut microbiota on renal tumor: a Mendelian randomization study'. International Journal of Surgery. 2024 Jan 15; Online ahead of print. (JCR Q1, IF 15.3)
• Zhu X, Huang B, Zhao J, Yin C, Li X, Zuo J, Chen J, Bao H. A commentary on 'Complex causal association between genetically predicted 731 immunocyte phenotype and osteonecrosis: a bidirectional two-sample Mendelian randomization analysis'. International Journal of Surgery. (JCR Q1, IF 15.3)
• Zhu X, He J, Chen J. A commentary on 'Genetically proxied intestinal microbiota and risk of bladder cancer'. International Journal of Surgery. (JCR Q1, IF 15.3)
• Chen B, Wang H, Xu H, Shi H, Zuo Y, Chen J, Feng W, Li Z. Renal cancer combined with prostate cancer with ureteral metastasis: a case report. Urology Case Reports. (JCR Q4, IF 0.5)
• Zhu X, Fu S, Chen J. Reevaluating the association between cholecystectomy and gastroesophageal reflux disease: recommendations for enhanced Mendelian randomization analysis. Annals of Medicine and Surgery (London). (JCR Q2, IF 1.7)
• Zhu X, Chen J, Zhao J. Commentary: Evaluation of the causal effects of immune cells on ischemic stroke: a Mendelian randomization study. Frontiers in Immunology. (JCR Q1, IF 5.9)
• Li X, Chen J, Wang J. Letter to the editor regarding 'Causal relationship between 731 immune cells and the risk of diabetic nephropathy: a two-sample bidirectional Mendelian randomization study'. Renal Failure. (JCR Q1, IF 3.0)
• Chen J, Wang H, Fu S. Response to Letter to the Editor on "Causal relationships between immune cells and erectile dysfunction based on Mendelian randomization". Sexual Medicine. (JCR Q1, IF 2.6)
• Zhan P, Chen W, Chen J, Zhao J, Ding M, Fu S, Wang J. Commentary: Exploring the gut microbiome and immunological landscape in kidney cancer: a Mendelian randomization analysis. Frontiers in Immunology. (JCR Q1, IF 5.9)
• Zhu X, Zhao J, Tang M, Fu S, Zuo J, Chen J. Letter to the editor on "No bidirectional association between serum 25-hydroxyvitamin D and erectile dysfunction: Mendelian randomization and genetic association studies". Sexual Medicine. (JCR Q1, IF 2.6)
• Zhu X, Liu R, Fu Y, Li D, Yang J, Chen B, Zuo J, Chen J, Li X. Insights and concerns on proteomic-based Mendelian randomization in ischemic stroke: the need for comprehensive data and methodological rigor. Annals of Medicine and Surgery (London). (JCR Q2, IF 1.7)
• Chen J, Li Z, Chen B, Zhao J, Zuo J, Wang H, Fu S. Case Report: Bladder endometriosis presenting as a bladder mass – diagnosis and surgical management. Frontiers in Surgery. (JCR Q1, IF 3.0)
• Zuo J, Chen J, Wang J. Reassessing the role of the gut microbiome in bladder cancer: a review of methodological approaches and future research directions. Urologic Oncology. (JCR Q2, IF 2.3)
• Zhao J, Chen J, Liu Z, Zhang W, Yao J. Strengthening causal inference between gut microbiota and prostate cancer: methodological considerations and recommendations. Urologic Oncology. (JCR Q2, IF 2.3)
• Chen P, Chen J, Fu S. Artificial intelligence and multi-modal data integration in renal cell carcinoma: a review of its potential and limitations. International Journal of Surgery. (JCR Q1, IF 10.1)
• Ye X, Chen J, Li H, Dong H, Wang H, Fu S. Comment on "U-shaped association between daily eating frequency and nighttime fasting duration and depression in NHANES 2005–2018". Journal of Affective Disorders. (JCR Q1, IF 4.9)
• Ji W, Fu M, Wang H, He Z, Chen J, Fu S, Fu Y, Zhu X. Case Report: Pregnancy complicated with pulmonary arteriovenous malformation – diagnosis and surgical management. Frontiers in Surgery. (JCR Q2, IF 1.8)
• Zhao J, Chen J, Yao J. Refining prognostic modeling in ureteral UTUC: integrating key confounders and nonlinearity: corresponding. International Journal of Surgery. (JCR Q1, IF 10.3)
• Chen J, Zhan P, Wang H, Fu S. Signet-ring cell carcinoma of the prostate: a case report. Asian Journal of Surgery. (JCR Q1, IF 3.8)

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