Dr. Samaila Musa Chiroma is a Senior Lecturer in Anatomy at Newcastle University Medicine Malaysia (NUMed). He holds a PhD in Human Anatomy (Neuroscience) from Universiti Putra Malaysia and Bachelor’s and Master’s degrees in Human Anatomy from University of Maiduguri, Nigeria. He is a Senior Fellow of the Higher Education Academy (SFHEA) and has completed a Postgraduate Certificate in Medical Education from Newcastle University, United Kingdom.

Dr. Chiroma’s research centers on neurodegenerative and neurobehavioral disorders, including Alzheimer’s disease, epilepsy, and depression. His work particularly investigates the neuroprotective potential of medicinal plants and plant-derived compounds. Using molecular, histological, and behavioral approaches, his research explores mechanisms related to oxidative stress, neuroinflammation, neurotransmitter dysregulation, and cognitive impairment.

He has held academic and postdoctoral research appointments in Nigeria and Malaysia and has published extensively in peer-reviewed international journals. His ongoing research advances translational approaches in neurotherapeutics, with a focus on plant-based interventions for epilepsy and neurodegeneration.

• Anatomy
• Ethnopharmacology
• Neurodegenerative Diseases
• Behavioural Neuroscience
• Medical Education

• Manoharan, S. D., Hamid, H. A., Hashim, N. F. M., Cheema, M. S., Chiroma, S. M., Mustapha, M., & Mehat, M. Z. (2024). Could protein phosphatase 2A and glycogen synthase kinase-3 beta be targeted by natural compounds to ameliorate Alzheimer’s pathologies? Brain Research, 148793.
• DİBAL, N., CHİROMA, M. S., ATTAH, M., & MANYE, S. (2024). Effects of Sub-acute Administration of Onion Waste Quercetin on the Hippocampus of Mice: A Histological Approach. Gazi University Journal of Science, 1-1.
• Vishnumukkala, T., Gopalakrishna, P. K., Jagadeesan, S., Chiroma, S. M., Nor, N. H. M., Baharuldin, M. T. H., ... & Moklas, M. A. M. (2024). Herbal Medicine: A Promising Approach for the Treatment of Alzheimer's Disease. International Journal of Ayurveda and Pharma Research, 142-150.
• Wana, M. N., Watanabe, M., Chiroma, S. M., Unyah, N. Z., Abdullahi, S. A., Nordin, S., ... & Abd Majid, R. (2023). Toxoplasma gondii induced cognitive impairment in rats via dysregulation of dopamine receptors and indoleamine 2, 3 dioxygenase. Heliyon.
• Bello, A. M., Salami, H. A., Malgwi, I. S., & Chiroma, S. M. (2023). Stem bark chloroform extract of Bombax costatum Pellegr. & Vuillet exhibit anticonvulsant and neuroprotective effects in pentylenetetrazole-induced seizures in rats. In Annales Pharmaceutiques Françaises (Vol. 81, No. 2, pp. 233-247).
• Farhani, N. I. B. R., Chiroma, S. M., Mohamad, T. A. S. T., & Mohd Moklas, M. A. (2023). Centella asiatica L. Urban protects against cognitive dysfunction in alluminum chloride-induced neurotoxicity in rats via inhibition of acetylcholinesterase level. Egyptian Journal of Basic and Applied Sciences, 10(1), 33-44.
• Muhammad, A., Hamman, L. L., Chiroma, S. M., Attah, M. O. O., & Dibal, N. I. (2023). Adansonia digitata L. Stem Bark Attenuates Epileptic Seizure, Depression, and Neurodegeneration by Mediating GABA and Glutamate in Pentylenetetrazol-Kindled Rats. Journal of pharmacopuncture, 26(4), 327.
• Muhammad Fannami, I., Hyedima Garba, S., Oliver Hamman, W., & Chiroma, S. M. (2023). Acute Toxicity Study of Methanol Extract of Baobab (Adansonia digitata Linn) Fruit Shell Extract in Mice. Pharmaceutical and Biomedical Research, 9(3), 201-210.
• Manye, S. J., Saleh, J. S., Ishaya, H. B., Chiroma, S. M., Attah, M. O. O., & Dibal, N. I. (2023). Phytochemical screening and in-vitro antioxidant activities of aqueous and methanol extracts of Aloe vera. Pharmacological Research-Modern Chinese Medicine, 8, 100291.
• Yusuf, Z. U., Dibal, N. I., & Chiroma, M. S. (2023). Iron Deficiency in Pregnancy: A Brief Review. Journal of Medical Science, 92(2), e776-e776.
• Ishaku, A. A., Bello, A. M., Dibal, N. I., & Chiroma, M. S. (2023). The Extract of Bombax Costatum Bark Improves Depression and Epileptic Seizures in Rats. Iranian Journal of Toxicology, 17(2), 95-104.
• Mailafiya, M. M., Abubakar, K., Chiroma, S. M., Danmaigoro, A., Zyoud, T. Y., Rahim, E. B. A., ... & Zakaria, Z. A. B. (2023). Curcumin‐loaded cockle shell‐derived calcium carbonate nanoparticles ameliorates lead‐induced neurotoxicity in rats via attenuation of oxidative stress. Food Science & Nutrition, 11(5), 2211-2231.
• Usman, H. A., Chiroma, S. M., Zirahei, J. V., & Dibal, N. I. (2023). Adansonia digitata L. fruit shell prevents aluminum-induced cognitive impairment and depression in mice. Brain Behavior and Immunity Integrative, 2, 100014.
• Mshelia, R. D. Z., Dibal, N. I., & Chiroma, S. M. (2023). Food irradiation: An effective but under-utilized technique for food preservations. Journal of Food Science and Technology, 60(10), 2517-2525.
• Dibal, N. I., Goni, Z. M., Attah, M. O. O., Imam, U., Abdullahi, M., Bashir, M., Chiroma, S. M., ... & Ishaya, H. B. (2023). Aloe vera Gel Ameliorates Fat-Rich and High Fructose (FRHF) Diet-Induced Pancreatic and Splenic Damage in Mice. Borneo Journal of Pharmacy, 6(3), 222-228.
• Fannami, I. M., Garba, S. H., & Chiroma, S. M. (2022). Adansonia digitata L. fruit shell extract alleviates lead-induced neurotoxicity in mice via modulation of oxidative stress and a possible chelating activity. Journal of Trace Elements in Medicine and Biology, 74, 127074.
• Bello, A. M., Malgwi, I. S., Adegoke, S. H., Abubakar, A. U., Ibrahim, B. M., & Chiroma, S. M. (2022). Oral acute toxicity study on stem bark extracts of Bombax costatum Pellegr. and Vuillet on wistar albino rats. Bulletin of the National Research Centre, 46(1), 254.
• Mustapha, S., Magaji, R. A., Magajic, M., Gayab, I. B., Yusha’ub, Y., & Chiroma, S. M. (2022). Rutin ameliorates lipopolysaccharide-induced depressive-like behaviours in mice model via inhibition of neuroinflammation. Journal of African Association of Physiological Sciences, 10(1), 67-77.
• Chiroma, S. S., Nazifi, A. B., Jamilu, Y. U., Musa, A., Bichi, L. A., & Chiroma, S. M. (2022). Anticonvulsant activity and mechanism of actions of fractions of Ipomoea asarifolia (Desr)(Convolvulaceae) ethanol leaf extract. Bulletin of the National Research Centre, 46(1), 1-9.
• Ishaya, P., Attah, M. O. O., Dibal, N. I., & Chiroma, M. S. (2022). Histomorphological and Morphometric Analysis of the Tongue in the Agama Lizard (Agama Agama), Toad (Bufo Bufo) and Rabbit (Oryctolagus Cuniculus Domesticus). Journal of Morphological Sciences Vol, 39, 88.
• Audu, H. A., Ahmed, A., Zirahei, J. V., Dibal, N. I., & Chiroma, S. M. (2022). Anogeissus leiocarpus (DC.) Guill and Perr ameliorates pentylenetetrazole-induced seizure/cognitive impairment in rats via inhibition of oxidative stress. Advances in Traditional Medicine, 1-10.
• Hauwa A, Ahmed A, Zirahei J. V., Chiroma S,M., & Dibal N.I (2022). Oral Acute Toxicity Study on Methanol Extracts of Anogeissus leiocarpus (DC.) Guill and Perr Stem Bark in Rats. Arid Zone Journal of Basic and Applied Research. 1(1), 201-209.
• Suliman, N. A., Moklas, M. A., Taib, C. N. M., Hidayat Baharuldin, M. T., & Chiroma, M. S. (2022). Erythroxylum cuneatum Prevented Cellular Adaptation in Morphineinduced Neuroblastoma Cells. Central Nervous System Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Central Nervous System Agents), 22(2), 108-117.
• Jagadeesan, S., Chiroma, S. M., Mohd Moklas, M. A., Hidayat Baharuldin, M. T., Mat Taib, C. N., Amom, Z., ... & Mahdi, O. (2022). Centella asiatica L. Urban protects against morphological aberrations induced by chronic unpredictable mild stress in rat’s hippocampus via attenuation of oxidative stress. Egyptian Journal of Basic and Applied Sciences, 9(1), 324-339.
• Ehi Oche, P., Isaac Dibal, N., Chiroma, S. M., & Orendu Oche Attah, M. (2022). Morphological and Morphometric Variations of Erythrocytes in Clarias Gariepinus, Bufo Bufo, and Agama Agama Using Some Histological Stains. Anatomical Sciences Journal, 19(1), 39-46.
• Chiroma, S. S., Nazifi, A. B., Ya’u, J., Aliyu, M., Bichi, L. A., & Chiroma, S. M. (2022). Anti-seizure properties of Ipomoea asarifolia (Desr.)(Convolvulaceae) ethanolic leaf extract in laboratory animals. Bulletin of the National Research Centre, 46(1), 1-7.
• Ishaya, L., DibaL, N. I., Chiroma, S. M., & Attah, M. O. O. (2021). Comparative Anatomical Study of the Kidneys in Cattle (Bos taurus) and Camel (Camelus dromederus). Journal of Morphological Sciences Vol, 38, 386.
• Mailafiya, M. M., Moklas, M. A., Abubakar, K., Danmaigoro, A., Chiroma, S. M., Rahim, E., & Zakaria, Z. A. (2021). Cytotoxicity studies of curcumin loaded-cockle shell-derived calcium carbonate nanoparticles. Nanoscience & Nanotechnology-Asia, 11(1), 35-41.
• Mahdi, O., Chiroma, S.M., Hidayat Baharuldin, M.T., Mohd Nor, N.H., Mat Taib, C.N., Jagadeesan, S., Devi, S. and Mohd Moklas, M.A., (2021). WIN55, 212-2 Attenuates Cognitive Impairments in AlCl3+ d-Galactose-Induced Alzheimer’s Disease Rats by Enhancing Neurogenesis and Reversing Oxidative Stress. Biomedicines, 9(9), p.1270.
• Aziz, N.U.A., Chiroma, S.M., Moklas, M.A.M., Adenan, M.I., Ismail, A., Basir, R., Ali, R.M. and Baharuldin, M.T.H.B., (2021). Menhaden fish oil attenuates postpartum depression in rat model via inhibition of NLRP3-inflammasome driven inflammatory pathway. Journal of traditional and complementary medicine, 11(5), pp.419-426.
• Mahdi, O., Baharuldin, M.T., Nor, N.H.M., Chiroma, S.M., Jagadeesan, S. and Moklas, M.A., (2021). The Neuroprotective Properties, Functions, and Roles of Cannabis sativa in Selected Diseases Related to the Nervous System. Central Nervous System Agents in Medicinal Chemistry, 21(1), pp.20-38.
• Abdul Aziz, N.U., Chiroma, S.M., Mohd Moklas, M.A., Adenan, M.I., Ismail, A. and Hidayat Baharuldin, M.T., (2020). Antidepressant-like properties of fish oil on postpartum depression-like rats model: involvement of serotonergic system. Brain sciences, 10(10), p.733.
• Li, L.S., Chiroma, S.M., Hashim, T., Adam, S.K., Moklas, M.A.M., Yusuf, Z. and Rahman, S.A., (2020). Antioxidant and anti-inflammatory properties of Erythroxylum cuneatum alkaloid leaf extract. Heliyon, 6(6), p.e04141.
• Mailafiya, M.M., Abubakar, K., Chiroma, S.M., Danmaigoro, A., Rahim, E.B.A., Moklas, M.A.M. and Zakaria, Z.A.B., (2020). Curcumin-loaded cockle shell-derived calcium carbonate nanoparticles: A novel strategy for the treatment of lead-induced hepato-renal toxicity in rats. Saudi Journal of Biological Sciences, 27(6), pp.1538-1552.
• Abubakar, K., Mailafiya, M. M., Chiroma, S. M., Danmaigoro, A., Zyoud, T. Y., Abdul Rahim, E., & Abu Bakar Zakaria, M. Z. (2020). Ameliorative effect of curcumin on lead‐induced hematological and hepatorenal toxicity in a rat model. Journal of biochemical and molecular toxicology, 34(6), e22483.
• Bulama, I., Nasiru, S., Bilbis, S. L., Abbas, A. Y., Nasiru, J. I., Saidu, Y., ... & Chiroma, M. S. (2020). Ascorbic acid treatment modulated traumatic brain injury-induced oxidative stress and neuropathic pain in rats. Journal of Cellular Neuroscience & Oxidative Stress, 12(1).
• Muhammad Mailafiya, M., Abubakar, K., Danmaigoro, A., Musa Chiroma, S., Bin Abdul Rahim, E., Aris Mohd Moklas, M., & Abu Bakar Zakaria, Z. (2019). Cockle shell-derived calcium carbonate (aragonite) nanoparticles: a dynamite to nanomedicine. Applied Sciences, 9(14), 2897.
• Abubakar, K., Muhammad Mailafiya, M., Danmaigoro, A., Musa Chiroma, S., Abdul Rahim, E. B., & Abu Bakar@ Zakaria, M. Z. (2019). Curcumin attenuates lead-induced cerebellar toxicity in rats via chelating activity and inhibition of oxidative stress. Biomolecules, 9(9), 453.
• Chiroma, S.M., Baharuldin, M.T.H., Mat Taib, C.N., Amom, Z., Jagadeesan, S., Ilham Adenan, M., Mahdi, O. and Moklas, M.A.M., (2019). Centella asiatica protects d-galactose/AlCl3 mediated Alzheimer’s disease-like rats via PP2A/GSK-3β signaling pathway in their Hippocampus. International journal of molecular sciences, 20(8), p.1871.
• Chiroma, S.M., Baharuldin, M.T.H., Taib, C.N.M., Amom, Z., Jagadeesan, S., Adenan, M.I. and Moklas, M.A.M., (2019). Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: Behavioral and ultrastructural approaches. Biomedicine & Pharmacotherapy, 109, pp.853-864.
• Chiroma, S.M., Baharuldin, M.T.H., Mat Taib, C.N., Amom, Z., Jagadeesan, S., Ilham Adenan, M., Mahdi, O. and Moklas, M.A.M., (2019). Protective effects of centella asiatica on cognitive deficits induced by D-gal/AlCl3 via inhibition of oxidative stress and attenuation of acetylcholinesterase level. Toxics, 7(2), p.19.
• Chiroma, S. M., Taib, C. N. M., Moklas, M. A. M., Baharuldin, M. T. H., Amom, Z., & Jagadeesan, S. (2019). The use of nootropics in Alzheimer’s disease: is there light at the end of the tunnel?. Biomedical Research and Therapy, 6(1), 2937-2944.
• Chiroma, S.M., Moklas, M.A.M., Taib, C.N.M., Baharuldin, M.T.H. and Amon, Z., (2018). D-galactose and aluminium chloride induced rat model with cognitive impairments. Biomedicine & Pharmacotherapy, 103, pp.1602-1608.
• Chiroma, S. M., Baharuldin, M. T. H., Taib, C. N. M., Amom, Z., Jagadeesan, S., & Moklas, M. A. M. (2018). Inflammation in Alzheimer’s disease: A friend or foe?. Biomedical Research and Therapy, 5(8), 2552-2564.
• Chiroma, S. M., Moklas, M. A. M., Norma, C. M., Taufik, M. H., Amon, Z., Jagadeesan, S., & Ibrahim, B. (2017). Neuro-therapeutic benefits of Centella asiatica on some neurodegenerative diseases: a review. Research Journal of Pharmaceutical Biological and Chemical Sciences, 8(6), 549-556.
• Orendu, A. M., Samaila, C. M., Ishaya, H. B., Paul, A., & Jacob, A. (2016). Measurement of obesity as indicated by body mass index using waist-hip ratio among apparently healthy students in University of Maiduguri, Nigeria. Nova, 5(3), 1-5.
• Attah, M. O., Suleiman, I. D., Samaila, M. C., Amaza, D. S., Ishaya, H. B., Balogun, S. U., ... & Jacks, T. W. (2015). A study of the ischiopubic index: A radiographic analysis in Maiduguri, North Eastern Nigeria. J Dent Med Sci, 14(8), 118-21.
• Chiroma, S. M., Attah, M. O., Taiwo, I. O., Buba, H. S., Dibal, N. I., & Jacks, T. W. (2015). Metric Analysis of the foot of yoruba students at the university of maiduguri, Nigeria. IOSR Journal of Dental and Medical Sciences, 14(8), 63-67.
• Chiroma, S. M., Philip, J., Attah, O. O., & Dibal, N. I. (2015). Comparison of the foot height, length, breadth and foot types between males and females Ga’anda people, Adamawa, Nigeria. IOSR J Dent Med Sci, 14(8), 89-93.

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