Dr. Hayato Takase is an Assistant Professor in the Department of Chemical Engineering at Miyazaki University, Japan. With a Ph.D. in Chemical Engineering, his research centers on the development of functional porous polymeric materials and their integration into advanced separation technologies—addressing core challenges in transport phenomena, unit operations, and sustainable process design.

Dr. Takase specializes in the synthesis and structural control of cryogel-based porous materials, with a focus on phase behavior, mass transfer efficiency, and interfacial engineering. Leveraging techniques such as the inverse Leidenfrost effect, he has established innovative methods for producing cryogel particles with tunable macro- and micro-porosity, enhancing their performance in key chemical engineering processes such as adsorption, filtration, and selective separation.

His cryogels have been applied in diverse fields, from oil-water separation systems and heavy metal ion recovery to biomolecule purification, demonstrating high selectivity, reusability, and process compatibility. He is also exploring the biomedical interface of chemical engineering through the development of biocompatible cryogel membranes for guided bone regeneration (GBR), expanding the scope of chemical product engineering into medical applications.

Dr. Takase has published extensively in high-impact journals, including ACS Applied Polymer Materials, ACS Omega, and Colloids and Surfaces B, and has presented his work at international conferences such as the AIChE Annual Meeting. He actively mentors students in experimental thermodynamics, phase equilibrium, and polymer processing, contributing to the next generation of chemical engineers.

• Functional Materials and Polymer Engineering:
• Design and synthesis of cryogel-based porous polymers
• Structural control of macroporous and hierarchical polymer networks
• Functionalization of polymer surfaces for targeted separation and biomedical applications
• Separation Processes and Transport Phenomena:
• Adsorptive separation and purification of biomolecules and metal ions
• Liquid-liquid and solid-liquid equilibrium in multicomponent systems
• Development of high-efficiency mass transfer media using porous materials
• Sustainable Chemical Engineering and Environmental Applications:
• Cryogel materials for oil-water separation and environmental remediation
• Upcycling of industrial and biomass-derived waste into functional materials
• Design of materials for energy-efficient and resource-recovery systems
• Bioengineering and Medical Applications:
• Development of biocompatible cryogel membranes for tissue engineering
• Porous scaffold design for guided bone regeneration (GBR)
• Interface between polymeric materials and biological environments
• Process Intensification and Advanced Fabrication Technologies:
• Utilization of the inverse Leidenfrost effect for novel material synthesis
• Integration of unique thermal and phase phenomena into material design
• Scalable fabrication techniques for industrial and biomedical materials

• Hayato Takase, Koichiro Shiomori, Yukihiro Okamoto, Nozomi Watanabe, Hideki Matsune, Hiroshi Umakoshi*, Micro Sponge Balls: Preparation and Characterization of Sponge-like Cryogel Particles of Poly(2-hydroxyethyl methacrylate) via the Inverse Leidenfrost Effect, ACS Appl. Polym. Mater, 2022, 4, 7081-7089.
• Hayato Takase, Keishi Suga, Hideki Matsune, Hiroshi Umakoshi*, Koichiro Shiomori*, Preferential Adsorption of L-Tryptophan by L-Phospholipid Coated Porous Polymer Particles, Colloids Surf. B, 2022, 216, Article No. 112535 (8 pages).
• Hayato Takase, Nozomi Watanabe, Koichiro Shiomori, Yukihiro Okamoto, Hideki Matsune, Hiroshi Umakoshi*, Versatility of the Preparation Method for Macroporous Cryogel Particles Utilizing the Inverse Leidenfrost Effect, ACS Omega, 2023, 8, 829-832.
• Endang Ciptawati* Hayato Takase, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hadi Nur, Hiroshi Umakoshi*, Preparation and Characterization of Biodegradable Sponge-like Cryogel Particles of Chitosan via the Inverse Leidenfrost (iLF) Effect, ACS Omega, 2024, 9, 2383-2390.
• Hayato Takase, Naoto Goya, Shiro Kiyoyama, Koichiro Shiomori, Hideki Matsune* Preparation of Hydrophobic Cryogel Containing Hydroxyoxime Extractant and Its Extraction Properties of Cu(Ⅱ), Gels, 2024, 9, Article No. 9
• Hayato Takase, Nozomi Watanabe, Koichiro Shiomori, Yukihiro Okamoto, Endang Ciptawati, Hideki Matsune, Hiroshi Umakoshi*, Preparation of Hydrophobic Monolithic Supermacroporous Cryogel Particles for the Separation of Stabilized Oil-in-Water Emulsion, Colloids Interfaces, 2023, 7, Article No. 9
• Junghu Lee, Noriko Yoshimoto, Hayato Takase, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi, Interaction Analysis between Cationic Lipid and Oligonucleotide with a Lipid Membrane-Immobilized Monolith Silica Column: A High-Performance Liquid Chromatography Approach, Langmuir, 2025, 4, 2214-2223.
• Jorgi Korleone, Elya Mufidah, Bambang Dwi Argo, Jocelyn Latreia ronauli Sidauruk, Hayato Takase, Ni’mutul Izza, Fine-Tuning Temulawak (Curcuma xanthorrhiza Roxb) Extraction: Solvent Selection, Methodological Approaches, and Optimization on Operating Condition, JKPTB, 2024, 3, 168-185.

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