Dr. Parvin Asadi

Current Affiliation:

Assistant Professor of Medicinal Chemistry.

^-Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran.

^-Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Science, Isfahan University of Medical Sciences, Isfahan, Iran.

Education

2011 – 2016: Isfahan University of Medical Sciences, Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences, Ph.D., medicinal Chemistry.

2007 – 2009: Isfahan University Of Technology, Department of Chemistry, M.Sc., Organic Chemistry.

2003 - 2007: Isfahan University Of Technology, Department of Chemistry, B.Sc., applied Chemistry.   

Prizes and Academic Honors

Distinguished Excellent Student award (in Ph.D. degree) in Iran, 2012.

Distinguished Excellent Student award (in Ms. Degree) in Iran, 2007-2009.

Distinguished Excellent Student award (in Bs. Degree) in Iran, 2003-2007.

• Synthesis of Biologycal Heterocycle Compounds
• Drug Design
• Covalent Organic Framework (COF)
• Polymer Synthesis
• Synthesis of Nanoparticles System

• Mehvari, F., Ramezanzade, V., Asadi, P., Singh, N., Kim, J., Dinari, M., & Kim, J. S. (2024). A panoramic perspective of recent progress in 2D and 3D covalent organic frameworks for drug delivery: Special Issue: Emerging Investigators. Aggregate, 5(2), e480.
• Asadi, P., Mahdie, F., Khodarahmi, G., Safaeian, L., &Hassanzade, F. (2024). Novel triazine-tyrosine hybrids containing thiyazol or pyridine fragment as anti-multiple sclerosis agents: Design, synthesis, biological evaluation, and molecular docking study. Heliyon, 10(19).
• Dinari, M., Golshadi, Z., Asadi, P., Norton, A. E., Reid, K. R., & Karimi, B. (2024). Recent progress on Covalent Organic frameworks supporting metal nanoparticles as Promising materials for Nitrophenol reduction. Nanomaterials, 14(17), 1458.
• Riyahi Z, Asadi P, Hassanzadeh F, Khodamoradi E, Gonzalez A, Abdolmaleki MK. Synthesis of novel conjugated benzofuran-triazine derivatives: Antimicrobial and in-silico molecular docking studies. Heliyon. 2023 Aug 1;9(8).
• Asadi P, Khodarahmi G, Rafiee A, Aliomrani M, Hassanzadeh F. Design, Synthesis, Bioactivity Analyses, and Molecular Docking Study of Triazine-Tyrosine Based Derivatives as Drugs like Fingolimod for Treatment of Multiple Sclerosis. Polycyclic Aromatic Compounds. 2023 May 30:1-20.
• Asadi P, Taymouri S, Khodarahmi G, Jalali H, Zaker H, Sadeghi‐Aliabadi H, Dinari M. Novel nanoscale vanillin based covalent triazine framework as a novel carrier for sustained release of imatinib. Polymers for Advanced Technologies. 2023 Apr;34(4):1358-66.
• Asadi P, Khodamoradi E, Khodarahmi G, Jahanian-Najafabadi A, Marvi H, Dehghan Khalili S. Novel N-α-amino acid spacer-conjugated phthalimide–triazine derivatives: synthesis, antimicrobial and molecular docking studies. Amino Acids. 2023 Jan 8:1-2.
• Hajhashemi V, Khodarahmi G, Asadi P, Rajabi H. Evaluation of the antinociceptive effects of a selection of triazine derivatives in mice. The Korean Journal of Pain. 2022 Oct 1;35(4):440-6.
• Saeidi S, Asadi P, Hassanzadeh F, Aliomrani M, Khodarahmi GA. Design and synthesis of some novel triazine-tyrosine hybrids as potential agents for the treatment of multiple sclerosis. Research in Pharmaceutical Sciences. 2022 Sep 13;17(5):482-92.
• Dinari M, Fardmanesh K, Maleki MH, Asadi P. Synthesis, characterization and antimicrobial properties of new L-cysteine based chiral aromatic polyamides. Polymer Bulletin. 2022 Dec 1:1-5.
• Mohebi M, Fayazi N, Esmaeili S, Rostami M, Bagheri F, Aliabadi A, Asadi P, Saghaie L. Synthesis, characterization, molecular docking, antimalarial, and antiproliferative activities of benzyloxy-4-oxopyridin benzoate derivatives. Research in pharmaceutical sciences. 2022 Jun;17(3):252.
• Asadi P, Khodamoradi E, Dinari M. Facile and fast preparation of layered double hydroxide as a nanocarrier for ascorbic acid under ultrasonic irradiation. Research in Pharmaceutical Sciences. 2022 Apr;17(2):143.
• Asadi P, Alvani M, Hajhashemi V, Rostami M, Khodarahmi G. Design, synthesis, biological evaluation, and molecular docking study on triazine based derivatives as anti-inflammatory agents. Journal of Molecular Structure. 2021 Nov 5;1243:130760.
• Malekzadeh M, Dadkhah S, Khodarahmi GA, Asadi P, Hassanzadeh F, Rostami M. Some novel hybrid quinazoline-based heterocycles as potent cytotoxic agents. Research in Pharmaceutical Sciences. 2022 Feb;17(1):22.
• Dadkhah S, Malekzadeh M, Hassanzadeh F, Khodarahmi G, Asadi P, Rostami M. The art of design in azlactone–benzoxazinone chemistry, docking studies and in vitro cytotoxicity evaluation. Australian Journal of Chemistry. 2022 Mar 16;75(4):312-23.
• Shahriyar S, Taymouri S, Saberi S, Asadi P, Tabbakhian M. Preparation and characterization of itraconazole loaded nanomicelles based on dextran–behenic acid for cutaneous leishmaniasis treatment. Drug Development and Industrial Pharmacy. 2021 Mar 4;47(3):416-28.
• Asadi P, Khodamoradi E, Dinari M. Facile and fast preparation of layered double hydroxide as a nanocarrier for ascorbic acid under ultrasonic irradiation. Research in Pharmaceutical Sciences. 2022 Apr;17(2):143.
• Asadi P, Falsafin M, Dinari M. Construction of new covalent organic frameworks with benzimidazole moiety as Fe3+ selective fluorescence chemosensors. Journal of Molecular Structure. 2021 Mar 5;1227:129546.
• Shirani MA, Maleki MH, Asadi P, Dinari M. Benzothiazolopyridine compounds: Facial synthesis, characterization, and molecular docking study on estrogen and progesterone receptors. Journal of Molecular Structure. 2021 Nov 5;1243:130792.
• Dinari M, Gharahi F, Asadi P. Synthesis, spectroscopic characterization, antimicrobial evaluation and molecular docking study of novel triazine-quinazolinone based hybrids. Journal of Molecular Structure. 2018 Mar 15;1156:43-50.
• Dinari M, Haghighi A, Asadi P. Facile synthesis of ZnAl-EDTA layered double hydroxide/poly (vinyl alcohol) nanocomposites as an efficient adsorbent of Cd (II) ions from the aqueous solution. Applied Clay Science. 2019 Mar 15;170:21-8.
• Khodarahmi G, Asadi P, Hassanzadeh F, Khodarahmi E. Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences. 2015 Nov;20(11):1094.
• Khodarahmi G, Asadi P, Farrokhpour H, Hassanzadeh F, Dinari M. Design of novel potential aromatase inhibitors via hybrid pharmacophore approach: docking improvement using the QM/MM method. RSC advances. 2015;5(71):58055-64.
• Asadi P, Khodarahmi G, Farrokhpour H, Hassanzadeh F, Saghaei L. Quantum mechanical/molecular mechanical and docking study of the novel analogues based on hybridization of common pharmacophores as potential anti-breast cancer agents. Research in Pharmaceutical Sciences. 2017 Jun;12(3):233.
• Asadi P, Khodarahmi G, Jahanian‐Najafabadi A, Saghaie L, Hassanzadeh F. Biologically active heterocyclic hybrids based on quinazolinone, benzofuran and imidazolium moieties: synthesis, characterization, cytotoxic and antibacterial evaluation. Chemistry & Biodiversity. 2017 Apr;14(4):e1600411
• Asadi P, Khodarahmi G, Jahanian-Najafabadi A, Saghaie L, Hassanzadeh F. Synthesis, characterization, molecular docking studies and biological evaluation of some novel hybrids based on quinazolinone, benzofuran and imidazolium moieties as potential cytotoxic and antimicrobial agents. Iranian journal of basic medical sciences. 2017 Sep;20(9):975.
• Dinari M, Asadi P. Thermal, mechanical and optical transport properties of nanocomposite materials based on triethoxysilane-terminated polyimide and TiO 2 nanoparticles. RSC advances. 2015;5(75):60745-53.
• Dinari M, Asadi P, Khajeh S. In situ thermal synthesis of novel polyimide nanocomposite films containing organo-modified layered double hydroxide: morphological, thermal and mechanical properties. New Journal of Chemistry. 2015;39(10):8195-203.
• Dinari M, Ahmadizadegan H, Asadi P. Fabrication and characterization of novel highly transparent and organo-soluble poly (ether imide) s thin film for gas separation. New Journal of Chemistry. 2015;39(6):4478-87.
• Mallakpour S, Asadi P. Structural features of bionanocomposite derived from novel designed poly (ester-imide) based on natural amino acids with hydroxyl segments tailored for better dispersion of TiO 2 nanofiller. Bulletin of Materials Science. 2013 Apr;36:203-12.
• Mallakpour S, Asadi P. Synthesis and structural characterization of novel bionanocomposite poly (ester-imide) s containing TiO2 nanoparticles, S-valine, and l-tyrosine amino acids moieties. Polymer bulletin. 2012 Jan;68(1):53-67.
• Mallakpour S, Asadi P, Sabzalian MR. Synthesis of biodegradable chiral poly (ester-imide) s derived from valine-, leucine-and tyrosine-containing monomers. Amino Acids. 2011 Nov;41:1215-22.
• Mallakpour S, Asadi P. Novel chiral poly (ester-imide) s with different natural amino acids in the main chain as well as in the side chain: synthesis and characterization. Colloid and Polymer Science. 2010 Aug;288(12-13):1341-9.

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